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Concerted Gating Mechanism Underlying K(ATP) Channel Inhibition by ATP
K(ATP) channels assemble from four regulatory SUR1 and four pore-forming K(ir)6.2 subunits. At the single-channel current level, ATP-dependent gating transitions between the active burst and the inactive interburst conformations underlie inhibition of the K(ATP) channel by intracellular ATP. Previou...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304061/ https://ncbi.nlm.nih.gov/pubmed/15041650 |
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