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Concerted Gating Mechanism Underlying K(ATP) Channel Inhibition by ATP

K(ATP) channels assemble from four regulatory SUR1 and four pore-forming K(ir)6.2 subunits. At the single-channel current level, ATP-dependent gating transitions between the active burst and the inactive interburst conformations underlie inhibition of the K(ATP) channel by intracellular ATP. Previou...

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Bibliografski detalji
Glavni autori: Drain, Peter, Geng, Xuehui, Li, Lehong
Format: Artigo
Jezik:Inglês
Izdano: Biophysical Society 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304061/
https://ncbi.nlm.nih.gov/pubmed/15041650
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