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Heteroaromatic analogs of the resveratrol analog DMU-212 as potent anti-cancer agents

Heteroaromatic analogs of DMU-212 (8–15) have been synthesized and evaluated for their anticancer activity against a panel of 60 human cancer cell lines. These novel analogs contain a trans-3,4,5-trimethoxystyryl moiety attached to the C2 position of indole, benzofuran, benzothiazole or benzothiophe...

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Publicat a:Bioorg Med Chem Lett
Autors principals: Penthala, Narsimha Reddy, Thakkar, Shraddha, Crooks, Peter A.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459527/
https://ncbi.nlm.nih.gov/pubmed/26022840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2015.05.019
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