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Synthesis and in vitro screening of novel N-benzyl aplysinopsin analogs as potential anticancer agents
A series of novel substituted (Z)-methyl 1-benzyl-3-((2,5-dioxoimidazolidin-4-ylidene)methyl)-1H-indoles (3a-f) and (Z)-5-((1-benzyl-1H-indol-3-yl)methylene)thiazolidine-2,4-diones (3g-o) have been synthesized utilizing microwave irradiation. These analogs were evaluated for in vitro cytotoxicity ag...
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| Publicado no: | Bioorg Med Chem Lett |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4400819/ https://ncbi.nlm.nih.gov/pubmed/21295476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.01.020 |
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