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Synthesis and in vitro screening of novel N-benzyl aplysinopsin analogs as potential anticancer agents

A series of novel substituted (Z)-methyl 1-benzyl-3-((2,5-dioxoimidazolidin-4-ylidene)methyl)-1H-indoles (3a-f) and (Z)-5-((1-benzyl-1H-indol-3-yl)methylene)thiazolidine-2,4-diones (3g-o) have been synthesized utilizing microwave irradiation. These analogs were evaluated for in vitro cytotoxicity ag...

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Vydáno v:Bioorg Med Chem Lett
Hlavní autoři: Penthala, Narsimha Reddy, Yerramreddy, Thirupathi Reddy, Crooks, Peter A
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400819/
https://ncbi.nlm.nih.gov/pubmed/21295476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.01.020
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