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Aplysinopsin Analogs: Synthesis and Anti-proliferative Activity of Substituted (Z)-5-(N-benzylindol-3-ylmethylene)imidazolidine-2,4-diones

A series of substituted (Z)-5-(N-benzylindol-3-ylmethylene)imidazolidine-2,4-dione (3) analogs structurally related to aplysinopsin, and that incorporate a variety of substituents in both the indole and N-benzyl moieties have been synthesized under microwave irradiation and conventional heating meth...

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Detalhes bibliográficos
Main Authors: Reddy, Y. Thirupathi, Reddy, P. Narsimha, Koduru, Srinivas, Damodaran, Chendil, Crooks, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3726003/
https://ncbi.nlm.nih.gov/pubmed/20403701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2010.03.054
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