Novel substituted (Z)-5-((N-benzyl-1H-indol-3-yl)methylene)imidazolidine-2,4-diones and 5-((N-benzyl-1H-indol-3-yl)methylene)pyrimidine-2,4,6(1H,3H,5H)-triones as potent radio-sensitizing agents

A series of (Z)-5-((N-benzyl-1H-indol-3-yl)methylene)imidazolidine-2,4-dione (9a–9m) and 5-((N-benzyl-1H-indol-3-yl)methylene)pyrimidine-2,4,6(1H,3H,5H)-trione (10a–10i) derivatives that incorporate a variety of aromatic substituents in both the indole and N-benzyl moieties have been synthesized. Th...

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Detalhes bibliográficos
Main Authors: Reddy, Y. Thirupathi, Sekhar, Konjeti R., Sasi, Nidhish, Reddy, P. Narsimha, Freeman, Michael L., Crooks, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159675/
https://ncbi.nlm.nih.gov/pubmed/20005706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.11.082
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