Antiangiogenic properties of substituted (Z)-(±)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-ol/one analogs and their derivatives

In the past half century research efforts have defined a critical role for angiogenesis in tumor growth and metastasis. We previously reported that inhibition of a novel target, ENOX1, by a (Z)-2-benzylindol-3-ylmethylene) quinuclidin-3-ol, suppressed tumor angiogenesis. The present study was undert...

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Main Authors: Venkateswaran, Amudhan, Reddy, Y. Thirupathi, Sonar, Vijaykumar N., Muthusamy, Venkatraj, Crooks, Peter A., Freeman, Michael L., Sekhar, Konjeti R.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3001633/
https://ncbi.nlm.nih.gov/pubmed/21055930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.10.060
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