Pharmacological and electrophysiological characterization of AZSMO-23, an activator of the hERG K+ channel

BACKGROUND AND PURPOSE: We aimed to characterize the pharmacology and electrophysiology of N-[3-(1H-benzimidazol-2-yl)-4-chloro-phenyl]pyridine-3-carboxamide (AZSMO-23), an activator of the human ether-a-go-go-related gene (hERG)-encoded K(+) channel (K(v)11.1). EXPERIMENTAL APPROACH: Automated elec...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Mannikko, R, Bridgland-Taylor, M H, Pye, H, Swallow, S, Abi-Gerges, N, Morton, M J, Pollard, C E
Format: Artigo
Sprog:Inglês
Udgivet: BlackWell Publishing Ltd 2015
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4459027/
https://ncbi.nlm.nih.gov/pubmed/25684549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13115
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