IRF-1 promotes liver transplant ischemia/reperfusion injury via hepatocyte IL-15/IL-15Rα production

Ischemia and reperfusion (I/R) injury following liver transplantation (LTx) is an important problem that significantly impacts clinical outcomes. Interferon regulatory factor-1 (IRF-1) is a nuclear transcription factor that plays a critical role in liver injury. Our objective was to determine the im...

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Publicado no:J Immunol
Main Authors: Yokota, Shinichiro, Yoshida, Osamu, Dou, Lei, Spadaro, Anthony V., Isse, Kumiko, Ross, Mark A., Stolz, Donna B., Kimura, Shoko, Du, Qiang, Demetris, Anthony J., Thomson, Angus W., Geller, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458432/
https://ncbi.nlm.nih.gov/pubmed/25964490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402505
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