IL-23 mediates murine liver transplantation ischemia-reperfusion injury via IFN-γ/IRF-1 pathway

Interleukin-23 (IL-23) is a proinflammatory cytokine initially studied in autoimmune disease that has been more recently linked to innate immunity. We observed that the expression of IL-23 is upregulated during hypoxia in a hepatocyte and nonparenchymal cell (NPC) coculture system, as well as during...

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Vydáno v:Am J Physiol Gastrointest Liver Physiol
Hlavní autoři: Klune, John R., Bartels, Christian, Luo, Jing, Yokota, Shinichiro, Du, Qiang, Geller, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6336948/
https://ncbi.nlm.nih.gov/pubmed/30307739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00231.2018
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