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Plasmacytoid Dendritic Cell-Derived IFN-α Promotes Murine Liver Ischemia/Reperfusion Injury Via Induction of Hepatocyte IRF-1

Plasmacytoid dendritic cells (pDC) constitute the body’s principal source of type I interferon (IFN) and are comparatively abundant in the liver. Among various cytokines implicated in liver ischemia and reperfusion (I/R) injury, type I IFNs have been described recently as playing an essential role i...

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Detalhes bibliográficos
Main Authors: Castellaneta, Antonino, Yoshida, Osamu, Kimura, Shoko, Yokota, Shinichiro, Geller, David A., Murase, Noriko, Thomson, Angus W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4077928/
https://ncbi.nlm.nih.gov/pubmed/24493010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27037
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