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Gut Bacteria Drive Kupffer Cell Expansion via MAMP-Mediated ICAM-1 Induction on Sinusoidal Endothelium and Influence Preservation-Reperfusion Injury after Orthotopic Liver Transplantation

Bacteria in the gut microbiome shed microbial-associated molecule patterns (MAMPs) into the portal venous circulation, where they augment various aspects of systemic immunity via low-level stimulation. Because the liver is immediately downstream of the intestines, we proposed that gut-derived MAMPs...

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Detalhes bibliográficos
Main Authors: Corbitt, Natasha, Kimura, Shoko, Isse, Kumiko, Specht, Susan, Chedwick, Lisa, Rosborough, Brian R., Lunz, John G., Murase, Noriko, Yokota, Shinichiro, Demetris, Anthony J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3532712/
https://ncbi.nlm.nih.gov/pubmed/23159949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.09.010
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