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SPRR2A enhances p53 deacetylation through HDAC1 and down regulates p21 promoter activity
BACKGROUND: Small proline rich protein (SPRR) 2A is one of 14 SPRR genes that encodes for a skin cross-linking protein, which confers structural integrity to the cornified keratinocyte cell envelope. New evidence, however, shows that SPRR2A is also a critical stress and wound repair modulator: it en...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3495018/ https://ncbi.nlm.nih.gov/pubmed/22731250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-13-20 |
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