The R280H X-Ray Cross-Complementing 1 Germline Variant Induces Genomic Instability and Cellular Transformation

X-ray Repair Cross Complementing protein 1 (XRCC1) plays an important role in base excision DNA repair (BER) as a scaffolding protein for BER enzymes. BER is one of the basic DNA repair pathways repairing greater than 20,000 endogenous lesions per cell per day. Proper functioning of XRCC1, one of th...

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Detaylı Bibliyografya
Yayımlandı:DNA Repair (Amst)
Asıl Yazarlar: Sizova, Daria V., Keh, Agnes, Taylor, Ben F., Sweasy, Joann B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4458331/
https://ncbi.nlm.nih.gov/pubmed/26011397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.05.005
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