Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions

Most cases of congenital obstructive nephropathy are the result of ureteropelvic junction obstructions, and despite their high prevalence, we have a poor understanding of their etiology and scarcity of genetic models. The eight-protein exocyst complex regulates polarized exocytosis of intracellular...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Fogelgren, Ben, Polgar, Noemi, Lui, Vanessa H., Lee, Amanda J., Tamashiro, Kadee-Kalia A., Napoli, Josephine Andrea, Walton, Chad B., Zuo, Xiaofeng, Lipschutz, Joshua H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457632/
https://ncbi.nlm.nih.gov/pubmed/26046524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129346
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