Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions

Most cases of congenital obstructive nephropathy are the result of ureteropelvic junction obstructions, and despite their high prevalence, we have a poor understanding of their etiology and scarcity of genetic models. The eight-protein exocyst complex regulates polarized exocytosis of intracellular...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Fogelgren, Ben, Polgar, Noemi, Lui, Vanessa H., Lee, Amanda J., Tamashiro, Kadee-Kalia A., Napoli, Josephine Andrea, Walton, Chad B., Zuo, Xiaofeng, Lipschutz, Joshua H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457632/
https://ncbi.nlm.nih.gov/pubmed/26046524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129346
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi