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Exocyst Sec10 protects epithelial barrier integrity and enhances recovery following oxidative stress, by activation of the MAPK pathway

Cell-cell contacts are essential for epithelial cell function, and disruption is associated with pathological conditions including ischemic kidney injury. We hypothesize that the exocyst, a highly-conserved eight-protein complex that targets secretory vesicles carrying membrane proteins, is involved...

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Detalhes bibliográficos
Main Authors: Park, Kwon Moo, Fogelgren, Ben, Zuo, Xiaofeng, Kim, Jinu, Chung, Daniel C., Lipschutz, Joshua H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2838587/
https://ncbi.nlm.nih.gov/pubmed/20053792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00596.2009
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