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Exocyst Sec10 protects renal tubule cells from injury by EGFR/MAPK activation and effects on endocytosis

Acute kidney injury is common and has a high mortality rate, and no effective treatment exists other than supportive care. Using cell culture models, we previously demonstrated that exocyst Sec10 overexpression reduced damage to renal tubule cells and speeded recovery and that the protective effect...

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Detalhes bibliográficos
Publicado no:Am J Physiol Renal Physiol
Main Authors: Fogelgren, Ben, Zuo, Xiaofeng, Buonato, Janine M., Vasilyev, Aleksandr, Baek, Jeong-In, Choi, Soo Young, Chacon-Heszele, Maria F., Palmyre, Aurélien, Polgar, Noemi, Drummond, Iain, Park, Kwon Moo, Lazzara, Matthew J., Lipschutz, Joshua H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4269694/
https://ncbi.nlm.nih.gov/pubmed/25298525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00032.2014
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