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Conformation of BCL-XL upon membrane-integration
BCL-XL is an anti-apoptotic BCL-2 family protein found both in the cytosol and bound to intracellular membranes. Structural studies of BCL-XL have advanced by deleting its hydrophobic C-terminus and adding detergents to enhance solubility. However, since the C-terminus is essential for function and...
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| Veröffentlicht in: | J Mol Biol |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457587/ https://ncbi.nlm.nih.gov/pubmed/25731750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.02.019 |
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