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Deletion of the App-Runx1 region in mice models human partial monosomy 21
Partial monosomy 21 (PM21) is a rare chromosomal abnormality that is characterized by the loss of a variable segment along human chromosome 21 (Hsa21). The clinical phenotypes of this loss are heterogeneous and range from mild alterations to lethal consequences, depending on the affected region of H...
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| Veröffentlicht in: | Dis Model Mech |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457029/ https://ncbi.nlm.nih.gov/pubmed/26035870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.017814 |
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