Deletion of the App-Runx1 region in mice models human partial monosomy 21

Partial monosomy 21 (PM21) is a rare chromosomal abnormality that is characterized by the loss of a variable segment along human chromosome 21 (Hsa21). The clinical phenotypes of this loss are heterogeneous and range from mild alterations to lethal consequences, depending on the affected region of H...

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Bibliografiske detaljer
Udgivet i:Dis Model Mech
Main Authors: Arbogast, Thomas, Raveau, Matthieu, Chevalier, Claire, Nalesso, Valérie, Dembele, Doulaye, Jacobs, Hugues, Wendling, Olivia, Roux, Michel, Duchon, Arnaud, Herault, Yann
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457029/
https://ncbi.nlm.nih.gov/pubmed/26035870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.017814
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