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Deletion of the App-Runx1 region in mice models human partial monosomy 21
Partial monosomy 21 (PM21) is a rare chromosomal abnormality that is characterized by the loss of a variable segment along human chromosome 21 (Hsa21). The clinical phenotypes of this loss are heterogeneous and range from mild alterations to lethal consequences, depending on the affected region of H...
Enregistré dans:
| Publié dans: | Dis Model Mech |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Company of Biologists
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4457029/ https://ncbi.nlm.nih.gov/pubmed/26035870 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.017814 |
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