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Molecular architecture and mechanism of the anaphase-promoting complex

The ubiquitination of cell cycle regulatory proteins by the anaphase-promoting complex/cyclosome (APC/C) controls sister chromatid segregation, cytokinesis and the establishment of G1. The APC/C is an unusually large multimeric cullin-RING ligase. Its activity is strictly dependent on regulatory coa...

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Publicat a:Nature
Autors principals: Chang, Lei-Fu, Zhang, Ziguo, Yang, Jing, McLaughlin, Stephen H., Barford, David
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456660/
https://ncbi.nlm.nih.gov/pubmed/25043029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13543
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