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Molecular architecture and mechanism of the anaphase-promoting complex
The ubiquitination of cell cycle regulatory proteins by the anaphase-promoting complex/cyclosome (APC/C) controls sister chromatid segregation, cytokinesis and the establishment of G1. The APC/C is an unusually large multimeric cullin-RING ligase. Its activity is strictly dependent on regulatory coa...
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| Pubblicato in: | Nature |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456660/ https://ncbi.nlm.nih.gov/pubmed/25043029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13543 |
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