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Molecular architecture and mechanism of the anaphase-promoting complex
The ubiquitination of cell cycle regulatory proteins by the anaphase-promoting complex/cyclosome (APC/C) controls sister chromatid segregation, cytokinesis and the establishment of G1. The APC/C is an unusually large multimeric cullin-RING ligase. Its activity is strictly dependent on regulatory coa...
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| Опубликовано в: : | Nature |
|---|---|
| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456660/ https://ncbi.nlm.nih.gov/pubmed/25043029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13543 |
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