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Experimental Correlation of Substrate Position with Reaction Outcome in the Aliphatic Halogenase, SyrB2

The iron(II)- and 2-(oxo)glutarate-dependent (Fe/2OG) oxygenases catalyze an array of challenging transformations, but how individual members of the enzyme family direct different outcomes is poorly understood. The Fe/2OG halogenase, SyrB2, chlorinates C4 of its native substrate, L-threonine appende...

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Foilsithe in:J Am Chem Soc
Main Authors: Martinie, Ryan J., Livada, Jovan, Chang, Wei-chen, Green, Michael T., Krebs, Carsten, Bollinger, J. Martin, Silakov, Alexey
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4456221/
https://ncbi.nlm.nih.gov/pubmed/25965587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b03370
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