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Experimental Correlation of Substrate Position with Reaction Outcome in the Aliphatic Halogenase, SyrB2
The iron(II)- and 2-(oxo)glutarate-dependent (Fe/2OG) oxygenases catalyze an array of challenging transformations, but how individual members of the enzyme family direct different outcomes is poorly understood. The Fe/2OG halogenase, SyrB2, chlorinates C4 of its native substrate, L-threonine appende...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4456221/ https://ncbi.nlm.nih.gov/pubmed/25965587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b03370 |
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