Determinants for degradation of SAMHD1, Mus81 and induction of G(2) arrest in HIV-1 Vpr and SIVagm Vpr

Vpr and Vpx are a group of highly related accessory proteins from primate lentiviruses. Despite the high degree of amino acid homology within this group, these proteins can be highly divergent in their functions. In this work, we constructed chimeric and mutant proteins between HIV-1 and SIVagm Vpr...

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Bibliografske podrobnosti
izdano v:Virology
Main Authors: DePaula-Silva, Ana Beatriz, Cassiday, Patrick A., Chumley, Jeffrey, Bosque, Alberto, Monteiro-Filho, Carlos M. R., Mahon, Cathal S., Cone, Kelsey R., Krogan, Nevan, Elde, Nels C., Planelles, Vicente
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455942/
https://ncbi.nlm.nih.gov/pubmed/25618414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.12.040
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