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SLX4-SLX1 Protein-independent Down-regulation of MUS81-EME1 Protein by HIV-1 Viral Protein R (Vpr)

Evolutionarily conserved structure-selective endonuclease MUS81 forms a complex with EME1 and further associates with another endonuclease SLX4-SLX1 to form a four-subunit complex of MUS81-EME1-SLX4-SLX1, coordinating distinctive biochemical activities of both endonucleases in DNA repair. Viral prot...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Zhou, Xiaohong, DeLucia, Maria, Ahn, Jinwoo
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016100/
https://ncbi.nlm.nih.gov/pubmed/27354282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.721183
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