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SLX4-SLX1 Protein-independent Down-regulation of MUS81-EME1 Protein by HIV-1 Viral Protein R (Vpr)

Evolutionarily conserved structure-selective endonuclease MUS81 forms a complex with EME1 and further associates with another endonuclease SLX4-SLX1 to form a four-subunit complex of MUS81-EME1-SLX4-SLX1, coordinating distinctive biochemical activities of both endonucleases in DNA repair. Viral prot...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Zhou, Xiaohong, DeLucia, Maria, Ahn, Jinwoo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5016100/
https://ncbi.nlm.nih.gov/pubmed/27354282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.721183
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