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Understanding the Molecular Manipulation of DCAF1 by the Lentiviral Accessory Proteins Vpr and Vpx

Vpr and Vpx are primate lentivirus proteins that manipulate the cellular CRL4 ubiquitin ligase complex. While Vpr is common to all primate lentiviruses, Vpx is only encoded by HIV-2 and a limited range of SIVs. Although Vpr and Vpx share a high degree of homology they are known to induce markedly di...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Virology
Prif Awduron: Cassiday, Patrick A., DePaula-Silva, Ana Beatriz, Chumley, Jeffrey, Ward, Jeffrey, Barker, Edward, Planelles, Vicente
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4323848/
https://ncbi.nlm.nih.gov/pubmed/25499532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.11.024
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