Determinants for degradation of SAMHD1, Mus81 and induction of G(2) arrest in HIV-1 Vpr and SIVagm Vpr

Vpr and Vpx are a group of highly related accessory proteins from primate lentiviruses. Despite the high degree of amino acid homology within this group, these proteins can be highly divergent in their functions. In this work, we constructed chimeric and mutant proteins between HIV-1 and SIVagm Vpr...

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Bibliografiske detaljer
Udgivet i:Virology
Main Authors: DePaula-Silva, Ana Beatriz, Cassiday, Patrick A., Chumley, Jeffrey, Bosque, Alberto, Monteiro-Filho, Carlos M. R., Mahon, Cathal S., Cone, Kelsey R., Krogan, Nevan, Elde, Nels C., Planelles, Vicente
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455942/
https://ncbi.nlm.nih.gov/pubmed/25618414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.12.040
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