Determinants for degradation of SAMHD1, Mus81 and induction of G(2) arrest in HIV-1 Vpr and SIVagm Vpr

Vpr and Vpx are a group of highly related accessory proteins from primate lentiviruses. Despite the high degree of amino acid homology within this group, these proteins can be highly divergent in their functions. In this work, we constructed chimeric and mutant proteins between HIV-1 and SIVagm Vpr...

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Publicado en:Virology
Autores principales: DePaula-Silva, Ana Beatriz, Cassiday, Patrick A., Chumley, Jeffrey, Bosque, Alberto, Monteiro-Filho, Carlos M. R., Mahon, Cathal S., Cone, Kelsey R., Krogan, Nevan, Elde, Nels C., Planelles, Vicente
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4455942/
https://ncbi.nlm.nih.gov/pubmed/25618414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.12.040
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