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Sex Influences SAMHD1 Activity and Susceptibility to Human Immunodeficiency Virus-1 in Primary Human Macrophages

BACKGROUND: Macrophages are major targets for HIV-1, contribute to viral propagation in vivo, and are instrumental in the pathogenesis of HAND. While it is known that host sex affects HIV-1 viremia and influences the severity of HIV-1-associated neurocognitive disease, a cellular or molecular basis...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Szaniawski, Matthew A, Spivak, Adam M, Bosque, Alberto, Planelles, Vicente
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6376916/
https://ncbi.nlm.nih.gov/pubmed/30299483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiy583
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