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Phylogenetic Insights into the Functional Relationship between Primate Lentiviral Reverse Transcriptase and Accessory Proteins Vpx/Vpr

The efficiency of reverse transcription to synthesize viral DNA in infected cells greatly influences replication kinetics of retroviruses. However, viral replication in non-dividing cells such as resting T cells and terminally differentiated macrophages is potently and kinetically restricted by a ho...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Main Authors: Sakai, Yosuke, Doi, Naoya, Miyazaki, Yasuyuki, Adachi, Akio, Nomaguchi, Masako
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5067338/
https://ncbi.nlm.nih.gov/pubmed/27803699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.01655
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