A carregar...
A [(32)P]-NAD(+)-based method to identify and quantitate long residence time enoyl-ACP reductase inhibitors
The classical methods for quantifying drug-target residence time (t(R)) use loss or regain of enzyme activity in progress curve kinetic assays. However, such methods become imprecise at very long residence times, mitigating the use of alternative strategies. Using the NAD(P)H-dependent FabI enoyl-AC...
Na minha lista:
| Publicado no: | Anal Biochem |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4454744/ https://ncbi.nlm.nih.gov/pubmed/25684450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2014.12.022 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|