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Temporal Expression Profiling Identifies Pathways Mediating Effect of Causal Variant on Phenotype

Even with identification of multiple causal genetic variants for common human diseases, understanding the molecular processes mediating the causal variants’ effect on the disease remains a challenge. This understanding is crucial for the development of therapeutic strategies to prevent and treat dis...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Gupta, Saumya, Radhakrishnan, Aparna, Raharja-Liu, Pandu, Lin, Gen, Steinmetz, Lars M., Gagneur, Julien, Sinha, Himanshu
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454590/
https://ncbi.nlm.nih.gov/pubmed/26039065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005195
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