Genotype-Environment Interactions Reveal Causal Pathways That Mediate Genetic Effects on Phenotype

Unraveling the molecular processes that lead from genotype to phenotype is crucial for the understanding and effective treatment of genetic diseases. Knowledge of the causative genetic defect most often does not enable treatment; therefore, causal intermediates between genotype and phenotype constit...

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Detalhes bibliográficos
Main Authors: Gagneur, Julien, Stegle, Oliver, Zhu, Chenchen, Jakob, Petra, Tekkedil, Manu M., Aiyar, Raeka S., Schuon, Ann-Kathrin, Pe'er, Dana, Steinmetz, Lars M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778020/
https://ncbi.nlm.nih.gov/pubmed/24068968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003803
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