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Temporal Expression Profiling Identifies Pathways Mediating Effect of Causal Variant on Phenotype

Even with identification of multiple causal genetic variants for common human diseases, understanding the molecular processes mediating the causal variants’ effect on the disease remains a challenge. This understanding is crucial for the development of therapeutic strategies to prevent and treat dis...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Gupta, Saumya, Radhakrishnan, Aparna, Raharja-Liu, Pandu, Lin, Gen, Steinmetz, Lars M., Gagneur, Julien, Sinha, Himanshu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4454590/
https://ncbi.nlm.nih.gov/pubmed/26039065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005195
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