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Genome-wide allele- and strand-specific expression profiling

Recent reports have shown that most of the genome is transcribed and that transcription frequently occurs concurrently on both DNA strands. In diploid genomes, the expression level of each allele conditions the degree to which sequence polymorphisms affect the phenotype. It is thus essential to quan...

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Bibliographic Details
Main Authors: Gagneur, Julien, Sinha, Himanshu, Perocchi, Fabiana, Bourgon, Richard, Huber, Wolfgang, Steinmetz, Lars M
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2710863/
https://ncbi.nlm.nih.gov/pubmed/19536197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2009.31
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