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Genotype-Environment Interactions Reveal Causal Pathways That Mediate Genetic Effects on Phenotype

Unraveling the molecular processes that lead from genotype to phenotype is crucial for the understanding and effective treatment of genetic diseases. Knowledge of the causative genetic defect most often does not enable treatment; therefore, causal intermediates between genotype and phenotype constit...

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Hlavní autoři: Gagneur, Julien, Stegle, Oliver, Zhu, Chenchen, Jakob, Petra, Tekkedil, Manu M., Aiyar, Raeka S., Schuon, Ann-Kathrin, Pe'er, Dana, Steinmetz, Lars M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778020/
https://ncbi.nlm.nih.gov/pubmed/24068968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003803
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