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It is not all about BRCA: Cullin-Ring ubiquitin Ligases in ovarian cancer

Mutations in the BRCA1 and BRCA2 genes predispose individuals to the development of breast and ovarian cancers. As a result, biochemical functions of BRCA1 and BRCA2 proteins are being characterised in great detail. These studies have prompted the use of PARP inhibitors to treat BRCA1 and BRCA2-defi...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Carlucci, A, D'Angiolella, V
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453745/
https://ncbi.nlm.nih.gov/pubmed/25490527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.594
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