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It is not all about BRCA: Cullin-Ring ubiquitin Ligases in ovarian cancer
Mutations in the BRCA1 and BRCA2 genes predispose individuals to the development of breast and ovarian cancers. As a result, biochemical functions of BRCA1 and BRCA2 proteins are being characterised in great detail. These studies have prompted the use of PARP inhibitors to treat BRCA1 and BRCA2-defi...
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| Veröffentlicht in: | Br J Cancer |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4453745/ https://ncbi.nlm.nih.gov/pubmed/25490527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.594 |
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