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MicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and -independent mechanisms

BACKGROUND: Colorectal cancers arise from benign adenomas, although not all adenomas progress to cancer and there are marked interpatient differences in disease progression. We have previously associated KRAS mutations with disease progression and reduced survival in colorectal cancer patients. METH...

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Publicat a:Br J Cancer
Autors principals: Amankwatia, E B, Chakravarty, P, Carey, F A, Weidlich, S, Steele, R J C, Munro, A J, Wolf, C R, Smith, G
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453675/
https://ncbi.nlm.nih.gov/pubmed/25919696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.125
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