MicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and -independent mechanisms

BACKGROUND: Colorectal cancers arise from benign adenomas, although not all adenomas progress to cancer and there are marked interpatient differences in disease progression. We have previously associated KRAS mutations with disease progression and reduced survival in colorectal cancer patients. METH...

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Xehetasun bibliografikoak
Argitaratua izan da:Br J Cancer
Egile Nagusiak: Amankwatia, E B, Chakravarty, P, Carey, F A, Weidlich, S, Steele, R J C, Munro, A J, Wolf, C R, Smith, G
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group 2015
Gaiak:
Translational Therapeutics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453675/
https://ncbi.nlm.nih.gov/pubmed/25919696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.125
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