MicroRNA-224 is associated with colorectal cancer progression and response to 5-fluorouracil-based chemotherapy by KRAS-dependent and -independent mechanisms

BACKGROUND: Colorectal cancers arise from benign adenomas, although not all adenomas progress to cancer and there are marked interpatient differences in disease progression. We have previously associated KRAS mutations with disease progression and reduced survival in colorectal cancer patients. METH...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Br J Cancer
Auteurs principaux: Amankwatia, E B, Chakravarty, P, Carey, F A, Weidlich, S, Steele, R J C, Munro, A J, Wolf, C R, Smith, G
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Translational Therapeutics
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453675/
https://ncbi.nlm.nih.gov/pubmed/25919696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.125
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires