O(6)-Methylguanine-DNA methyltransferase status in neuroendocrine tumours: prognostic relevance and association with response to alkylating agents

BACKGROUND: O(6)-Methylguanine-DNA methyltransferase (MGMT) loss of expression has been suggested to be predictive of response to temozolomide in neuroendocrine tumours (NETs), but so far, only limited data are available. We evaluated the prognostic and predictive value of MGMT status, assessed by t...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Walter, T, van Brakel, B, Vercherat, C, Hervieu, V, Forestier, J, Chayvialle, J-A, Molin, Y, Lombard-Bohas, C, Joly, M-O, Scoazec, J-Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Translational Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453664/
https://ncbi.nlm.nih.gov/pubmed/25584486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.660
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados