Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy

Neuropathic pain treatment remains a challenge because pathomechanism is not fully understood. It is believed that glial activation and increased spinal nociceptive factors are crucial for neuropathy. We investigated the effect of parthenolide (PTL) on the chronic constriction injury to the sciatic...

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Dettagli Bibliografici
Pubblicato in:Neural Plast
Autori principali: Popiolek-Barczyk, Katarzyna, Kolosowska, Natalia, Piotrowska, Anna, Makuch, Wioletta, Rojewska, Ewelina, Jurga, Agnieszka M., Pilat, Dominika, Mika, Joanna
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452088/
https://ncbi.nlm.nih.gov/pubmed/26090236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/676473
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