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Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy

Neuropathic pain treatment remains a challenge because pathomechanism is not fully understood. It is believed that glial activation and increased spinal nociceptive factors are crucial for neuropathy. We investigated the effect of parthenolide (PTL) on the chronic constriction injury to the sciatic...

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Detalhes bibliográficos
Publicado no:Neural Plast
Main Authors: Popiolek-Barczyk, Katarzyna, Kolosowska, Natalia, Piotrowska, Anna, Makuch, Wioletta, Rojewska, Ewelina, Jurga, Agnieszka M., Pilat, Dominika, Mika, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452088/
https://ncbi.nlm.nih.gov/pubmed/26090236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/676473
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