Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy

Neuropathic pain treatment remains a challenge because pathomechanism is not fully understood. It is believed that glial activation and increased spinal nociceptive factors are crucial for neuropathy. We investigated the effect of parthenolide (PTL) on the chronic constriction injury to the sciatic...

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Dades bibliogràfiques
Publicat a:Neural Plast
Autors principals: Popiolek-Barczyk, Katarzyna, Kolosowska, Natalia, Piotrowska, Anna, Makuch, Wioletta, Rojewska, Ewelina, Jurga, Agnieszka M., Pilat, Dominika, Mika, Joanna
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4452088/
https://ncbi.nlm.nih.gov/pubmed/26090236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/676473
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