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Delta-Opioid Receptor Analgesia Is Independent of Microglial Activation in a Rat Model of Neuropathic Pain

The analgesic effect of delta-opioid receptor (DOR) ligands in neuropathic pain is not diminished in contrast to other opioid receptor ligands, which lose their effectiveness as analgesics. In this study, we examine whether this effect is related to nerve injury-induced microglial activation. We the...

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Detalhes bibliográficos
Main Authors: Mika, Joanna, Popiolek-Barczyk, Katarzyna, Rojewska, Ewelina, Makuch, Wioletta, Starowicz, Katarzyna, Przewlocka, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126741/
https://ncbi.nlm.nih.gov/pubmed/25105291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104420
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