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Delta-Opioid Receptor Analgesia Is Independent of Microglial Activation in a Rat Model of Neuropathic Pain

The analgesic effect of delta-opioid receptor (DOR) ligands in neuropathic pain is not diminished in contrast to other opioid receptor ligands, which lose their effectiveness as analgesics. In this study, we examine whether this effect is related to nerve injury-induced microglial activation. We the...

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Bibliografiske detaljer
Main Authors: Mika, Joanna, Popiolek-Barczyk, Katarzyna, Rojewska, Ewelina, Makuch, Wioletta, Starowicz, Katarzyna, Przewlocka, Barbara
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4126741/
https://ncbi.nlm.nih.gov/pubmed/25105291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104420
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