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Protein Kinase C enhances human sodium channel hNav1.7 resurgent currents via a serine residue in the domain III–IV linker
Resurgent sodium currents likely play a role in modulating neuronal excitability. Here we studied whether protein kinase C (PKC) activation can increase resurgent currents produced by the human sodium channel hNav1.7. We found that a PKC agonist significantly enhanced hNav1.7-mediated resurgent curr...
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| Udgivet i: | FEBS Lett |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4451938/ https://ncbi.nlm.nih.gov/pubmed/25240195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2014.09.011 |
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